Angelica Chalcone from TaKaRa Bio

Angelica & Soy Germ Extract

(Product of Japan)

Angelica Chalcone capsules from TaKaRa Bio contain unique polyphenol extracts - or ‘chalcones’ - from the leaves of Angelica keiskei, known in Japan as Ashitaba, together with soybean extracts.

 

What is Angelica keiskei (‘Ashitaba’ in Japanese)?

Angelica keiskei (Ashitaba) is a traditional vegetable in Japan which is from the Apiaceae Angelica family.  This Angelica keiskei herb is grown along the Pacific coast of Japan and used as a folk medicine and for health-promoting foods for centuries in this country. This vegetable has high contents of protein, vitamins A, B, E and K, carotene, potassium, pantothenic acid, niacin, and dietary fiber. Furthermore, it abundantly contains various chalcones, flavanones and cumarins in its roots, stems and leaves.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Angelica keiskei (Ashitaba)               Yellow sap from harvested Angelica keiskei

 

 

Chalcones from Angelica keiskei under scientific investigation for their beneficial bioactivities

Chalcones are naturally occurring flavonoids and synthesized from malonyl CoA and cinnamic acid by chaconne synthase in higher plants. They are the starting material for flavonoids, such as flavanone, flavonol, isoflavone, catechin and anthocyanidin. Chalcones have a very limited distribution in edible plants; they mainly occur in Angelica  keiskei, hops, licorice and safflower.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Structures of chalcones from Angelica keiskei. The two major chalcones 4-Hydroxyderricin (4HD) and Xanthoangelol (XA) and further six newly discovered chalcones

 

Angelica keiskei and its chalcones have been researched extensively for its bioactive benefits for decades. Many studies worldwide have found chalcones derived from Angelica keiskei may have the abilities to assist quality of life.

 

Information about most of the research studies on Angelica keiskei’s chalcones can be found at Pubmed, a free search engine accessing references and abstracts on life sciences and biomedical topics. https://www.ncbi.nlm.nih.gov/pubmed/

 

Here are links to some of the very interesting articles:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435568/pdf/IEMAMC-13-185.pdf

https://www.jstage.jst.go.jp/article/bbb/76/5/76_110976/_pdf

https://www.jstage.jst.go.jp/article/bbb/76/5/76_110927/_pdf

https://www.jstage.jst.go.jp/article/jcam/9/1/9_1_49/_pdf

 

 

 

 

 

 

 

 

 

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